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Removal of these contacts by GCGR triple mutant (Q142A + D195A + R199A) markedly reduced peptide 20 potency by 93-fold (Fig

All GLP-1 receptor agonists studied semaglutide (Wegovy, Ozempic), tirzepatide (Mounjaro), liraglutide (Saxenda, Victoza) show the same class effect on biliary disease

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