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This heterogeneity and poorly understood neurobiology pose significant challenges to existing drug development paradigms, resulting in scarce treatment options, especially for bipolar depression

If metformin-associated lactic acidosis is suspected, immediately discontinue JANUMET and institute general supportive measures in a hospital setting

However, glucagon can stimulate energy expenditure in species with little BAT (adult dogs) or no BAT (pigs) activity

We can now address all manner of concerns from common ailments, from intestinal parasites to once incurable conditions like blindness

Providing information about clinical efficacy and potential cost offsets helps make the case for coverage expansion

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