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Presented for research literature review only Boivin P et al

Less Common Localized swelling Blood sugar fluctuations These typically resolve with continued use or dose adjustment

1 Introduction Solid tumors are made up of tumor cells and the tumor microenvironment (TME) that includes various cells (immune cells and mesenchymal cells) and extracellular matrix (ECM) ( With the development of nanotechnology and the wide application of nano-loaded materials in the treatment of diseases, the nano-drug co-delivery system has shown strong advantages in the delivery of drugs, natural active ingredients and genes, such as improving the water solubility of loaded drugs, prolonging the drug cycle time, controlling the slow release of drugs and targeting tumors, and based on these properties of drug-loaded nanosystems make them show a wide range of applications in the treatment of tumors ( Figure 1 )

Aroma refers to an ingredient, or mixture of ingredients, that impart or mask a flavor

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Effect of the normal microbial flora on gastrointestinal motility