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Because three receptor systems are involved, reducing the dose to manage side effects may disproportionately affect one pathway more than others, leading to unpredictable changes in the benefit profile

Normally, the rate of thyroid hormone production is controlled by the brain by the pituitary gland

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They lower blood sugar through several coordinated effects, including 13: Increasing insulin release when blood sugar rises Reducing glucagon, which would otherwise raise blood sugar Slowing gastric emptying, which helps limit post-meal spikes Because these effects are glucose-dependent, the risk of hypoglycemia is relatively low compared to some other diabetes medications

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Vitamin C prevents DNA mutation induced by oxidative stress