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In rare cases, GLP-1based therapies have been associated with pancreatitis, a serious condition involving inflammation of the pancreas

Protein set analyses found that semaglutide treatment downregulated proteins involved in key biological pathways governing xenobiotic metabolism, fatty acid metabolism and mammalian target of rapamycin complex 1 (MTORC1) signaling, among others (Extended Data Fig

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Excess body weight and gastroesophageal reflux disease

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