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The limited success of immunotherapy in solid tumors arises from several key challenges: The immunosuppressive and hypoxic TME impairs T cell proliferation, differentiation, and effector functions
While GLP-1 therapies such as Ozempic, Wegovy, Mounjaro and Zepbound are already well established in the Canadian market, the report notes that the 2026 pipeline reflects a focus on improved efficacy, more uses and longer dosing intervals
Excess weight can contribute to facial fat deposits, skin laxity, and accelerated aging
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