Neuropsychiatr Dis Treat 19:125 Smith GS, Oeltzschner G, Gould NF et al (2021) Neurotransmitters and Neurometabolites in Late-Life Depression: A Preliminary Magnetic Resonance Spectroscopy Study at 7T
3 mo trial avg 9lbs 6 mo trial avg 18lbs 12 mo trial avg 28lbs BMI is an estimate, not a diagnosis, and may not reflect health for athletes, pregnant women, children, older adults, or certain ethnic backgrounds
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Phase 3 trials are currently ongoing and will provide data on longer treatment durations, maintenance protocols, and discontinuation outcomes specific to retatrutide
There have yet to be studies directly comparing tirzepatide vs semaglutide in this subgroup of patients
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