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Discontinuation rates range from 37% to 81% within the first year, driven by cost, side effects, and access barriers, with weight regain thereafter mediated through hormonal dysregulation, CNS maladaptation to reduced GLP-1 signaling, and -cell dysfunction
Another app, MeAgain , uses photo overlays to compare your current progress photos with earlier ones, highlighting subtle changes in body composition that a scale might miss
The error has been fixed in the paper
10.1038/s44161-022-00094-w 208
Patients tend to regain weight following cessation of elite behavior, this is why long-lasting management strategies are brought up during medical visits
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