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After filtration, this total was reduced by approximately one order of magnitude, yielding 594 significantly upregulated and 90 significantly downregulated proteins in ischemic myocardial sections from animals given semaglutide

Moreover, besides the enhanced activity of fibroblasts, which are considered essential for collagen synthesis, tissue repair, and regeneration, there was also a potential rise in mast cell activation

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Nauck MA, Heimesaat MH, Behle K, Holst JJ, Nauck MAS, Hfner M, Schmiegel WH

Instability challenges and stabilization strategies of pharmaceutical proteins

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