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Additionally, IR increases the endometrial inflammatory milieu by promoting the activation of natural killer (NK) cells and skewing macrophages toward the M2 anti-inflammatory phenotype (Liu S

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2.4 Other Diseases Oxidative damage caused by overactivation of the immune response is the key pathogenic factor of chronic inflammation conditions, such as Crohns disease (CD), rheumatoid arthritis, and the inflammatory bowel diseases (Hussain et al., 2016

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The third approach focuses on targeting oxidative stress, inflammation, and fibrosis