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Patients who are pregnant or breastfeeding, patients with active malignancy, patients with certain vascular conditions where angiogenesis is a concern, and patients on specific anticoagulants may not be candidates

PMID 29155147

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Run 6-8 weeks on, then take 4-6 weeks off

This dual-axis attack on energy balance simultaneously reducing input and increasing output may be responsible for the sustained slope of weight loss that was not observed with single or dual-agonist compounds in comparable timelines

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