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This is why working with averages is so much easier than explaining variablity around the average
Wegovy (approved for weight loss) experienced months-long shortages that ended in December 2022, at which point first-time on-label prescribing increased sharply
Proper injection technique, alcohol swabs, and sharps disposal containers are essential
Patients sometimes try to order a higher dose after a long break, perhaps to "stock up" or to speed up their results
Weight stagnation doesn't indicate a safety issue
This observation corroborates our previous finding, that an amino acid change to proline in that region of DIII supported this natural bend and prevented the transition into postfusion conformation and therefore inhibited membrane fusion 16
