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2004 May 15;92(2):285-95

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Finally, key disease phenotypes of the Mmut p.L690Ins/p.L690Ins mice, such as weight loss, were not rescued by BCATi, in contrast with complete rescue in response to replacement of the defective Mmut gene with the normal human MMUT gene via an AAV construct, as shown here and previously in other murine MMA models (37)

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Additionally, the reassurance of doctors is important, and they should openly address questions related to a patients prognosis