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Altogether, our SwissKASH system shows that local S-palmitoylation of Go can cause its in-situ accumulation in the signaling-competent form, indicating that zDHHC selectivity and subcellular localization are key players in the substrate compartmentalization of the G protein, and potentially PMPs in general
These peptides are not intended for human consumption, medical treatment, veterinary applications, or any use outside controlled research environments
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