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Together, these actions may contribute to better bowel regularity and less straining, especially for those with chronic or idiopathic constipation

Human clinical evidence remains limited

Some reactions take time to develop, and daily application may trigger responses that alternate-day use didn't reveal

Homocysteine levels rise when enough Vitamin B12 antibodies are not present

Symptoms can range from abdominal pain and cramping to fever, nausea, and changes in bowel habits

The one cancer signal in the literature is not reassuring : in a study of gastrointestinal stromal tumors, higher levels of thymosin beta-4 tracked with more aggressive disease and worse outcomes