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If the weight-loss benefit of amylin biology comes from the amylin receptor and the tolerability cost comes partly from off-target activity, then a cleaner molecule should in theory separate the two

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It is considered a triple hormone agonist that works on 3 different receptors: glucagon-like peptide-1 receptor (GLP-1), glucagon receptor (GCG), and glucose-dependent insulinotropic polypeptide receptor (GIP)