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The FDA approved Ozempic in December 2017 for type 2 diabetes treatment, but the agency didnt add ileus warnings to the label until September 2023 nearly six years after approval
Still, GLP-1s work best in partnership with healthy habits for weight management, like a nutritious diet, adequate sleep, stress management, and moderate physical activity
Monti and colleagues in Uruguay ran a double-blind crossover of 25 nmol/kg over four nights and found that although several sleep measures moved in the expected direction, none differed significantly from baseline or placebo, and where differences did reach significance for NREM and stage 2 sleep, the same differences already existed at baseline
But if the good versus evil axis gets out of whack and there are more free radicals in the body than antioxidants, it results in a condition called oxidative stress
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