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While AOD-9604 is not FDA-approved as a prescription drug, it has received GRAS (Generally Recognized as Safe) status, indicating low toxicity and a good safety profile

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Progressive Fat Loss Phase (Weeks 4-12): The most significant body composition improvements typically occur between weeks four and twelve of consistent AOD-9604 use

According to Kannt & Pfenninger in Frontiers in Physiology , NAD is a critical coenzyme in mitochondrial energy metabolism, and strategies that preserve NAD have wide-ranging effects on health and performance (Kannt & Pfenninger, Frontiers in Physiology )

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Data are lacking from long-term studies to assess whether oral treatment is effective when doses are administered less frequently than daily