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Vegetarians, vegans, the elderly, individuals who regularly consume alcohol, and people suffering from Crohns disease or celiac disease are at a higher risk of developing a vitamin B12 deficiency

The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages

Rare anaphylactoid symptoms (facial pallor, blood pressure drop) may occur, so monitor the patient closely, and avoid nerves and blood vessels during IM injection

What spoiled B12 looks like A vial that is cloudy, discoloured, has visible particles or an unusual smell should not be used

Consumers and practitioners may misinterpret GRAS approval as evidence of efficacy, when in fact the obesity trialthe only controlled efficacy studywas negative

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