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The combination of GSTM1 active and GSTT1 active genotype decreased the risk of ASD (OR = 0.126, 95%CI: 0.0290.547, p = 0.006), as well as combination of GSTT1 active and GSTP1 llelle (OR = 0.170, 95%CI: 0.0290.992, p = 0.049)

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Caspase-1, an inflammatory mediator, can activate pro-inflammatory cytokines (IL-1 and IL-18) and participate in the initiation of inflammation [83]

My GP has (eventually) referred me to both a rheumatologist and an endocrinologist for further investigations, so perhaps that will throw some light on the matter

Koyanagi and S