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The baseline-dependent response, while mechanistically informative, also constrains generalizability, as the intervention may be ineffective in individuals with low endogenous A
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Engaging in healthy lifestyle choices, such as regular exercise, a balanced diet, and sufficient sleep, can also support physical and mental health during this period
In general, the hypermethylation of specific gene regions can silence protective genes, whereas hypomethylation may activate pathogenic pathways 26
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