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However, its explicit role in the Y-H transition is yet to be explored [121]
Massie, R
In these reactions GSH is oxidized to GSSG and the ratio [GSH]/[GSSG], an indicator of the redox status of the cell, is known to regulate redox sensitive enzymes in the pathways for cell proliferation and cell apoptosis [5]
The critical practical point is that these two mechanisms are complementary, not redundant
CD38 inhibition, resulting in increased NAD + levels, may slow aspects of the aging trajectory and enhance immune function, making it a promising area of research for various diseases 137,138
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