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The histidine residues provide a tertiary structural interaction with the two domains of PrP and copper, that is also protective in function due to involvement of the conserved central region of the protein (Roseman et al., 2020)

PTSD + MDD ( n = 18) and PTSD only ( n = 7) participants did not differ in circulating levels of MMP-9 ( p = 0.282), TIMP-1 ( p = 0.394), nor TIMP-2 ( p = 0.784)

These health amendments might occur because of the reduction of oxidative stress

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