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Furthermore, many patients prescribed tirzepatide for type 2 diabetes are concurrently taking metformin, which independently increases the risk of vitamin B12 deficiency through impaired calcium-dependent B12-intrinsic factor uptake in the ileum
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Because federal rules now limit when compounded copies of semaglutide and tirzepatide can be made, a careful provider will document a specific clinical reason a compounded option is right for you (FDA)
Published 2021 Jul 7
Adverse events related to hyperkalemia were generally manageable with appropriate potassium monitoring and dose adjustments [14, 76]
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