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In clinical practice, this effect is generally modest and does not significantly compromise antibiotic efficacy
Derewenda Z., 1994
Trimethylamine N-oxide: a link among diet, gut microbiota, gene regulation of liver and intestine cholesterol homeostasis and HDL function
Xu G, Kaneto H, Lopez-Avalos MD, Weir GC, and Bonner-Weir S
* **Diabetic Retinopathy Complications:** In patients with Type 2 Diabetes, very rapid improvements in blood sugar control can occasionally lead to a temporary worsening of existing diabetic eye disease
It is currently in late-stage clinical trials (phase 3) and has not received a marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)
