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Despite robust associations between the microbiome and CFS/ME, causality is difficult to establish due to confounding factors such as diet, medication use, and reduced physical activity

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A recent Phase 2 randomised placebo-controlled trial tested efinopegdutide in people with obesity over a 26-week period, where participants were randomly assigned weekly treatment with either placebo, 5 mg, 7.4 mg, 10 mg efinopegdutide, or 3 mg liraglutide daily

Signs of allergic reaction include widespread hives or rash, swelling of the face, lips, or throat, difficulty breathing, rapid heartbeat, and dizziness or loss of consciousness

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Weight loss from Saxenda can indirectly improve hormonal balance, particularly in conditions like PCOS, and may restore more regular menstrual cycles