A study showed that around 70% of the GH released during sleep promotes slow-wave sleep
doi:10.1002/14651858.CD008650.pub2
The contents of these compounds are comprised of total phenolics (0.0485%), total polysaccharides (21.6%), total flavonoids (0.235%), total amino acids (1.92%), sitosterol (0.113%), and other undetermined compounds (77.8%) (Zhan et al., 2016)
No direct retatrutide-versus-tirzepatide randomised controlled trial has been published or announced as of April 2026
However, significant weight losswhich these medications facilitatecan naturally improve testosterone levels in men who were previously overweight, potentially reducing your need for replacement therapy over time
MOTS-c is also the better starting point for patients who want to support physical performance and recovery, because it acts as what researchers describe as an exercise mimetic, activating some of the same cellular pathways that exercise triggers