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These agents mimic the biological action of the native incretin hormone GLP-1 but are structurally modified to resist degradation by the enzyme dipeptidyl peptidase 4 (DPP-4), thereby extending their half-life and duration of action (Zheng et al., 2024
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Understanding that Semaglutide acts directly on the liver's internal architecture, independent of weight loss, is a massive shift for metabolic therapy
Liraglutide modulates gut microbiota and reduces NAFLD in obese mice
Boehringer Ingelheim International
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