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Randomized trials monitoring GLP-1 agonists for cardiovascular and metabolic outcomes have not flagged increased cancer risk in interim safety analyses

Mancini GBJ, OMeara E, Zieroth S, Bernier M, Cheng AYY, Cherney DZI, et al

Turk BE, Huang LL, Piro ET, Cantley LC: Determination of protease cleavage site motifs using mixture- based oriented peptide libraries

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A conservative estimate suggests that a 50-pound weight regain costs $5,000 to $15,000 in direct healthcare costs over the following five years through increased medications, more frequent provider visits, and management of weight-related complications