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Another approved use for Ozempic is to reduce the risk of major cardiovascular disease, like heart attack or stroke, in adults with type 2 diabetes with known heart disease
Similarly, while cardiovascular protection is consistently observed, the extent to which this arises from direct receptor signaling in cardiomyocytes versus indirect systemic effects remains debated
Drug Interactions and Combination Risks Neither peptide has been studied in formal drug interaction trials
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Huang Y, Cao S, Zhang Q, Zhang H, Fan Y, Qiu F, Kang N (2018) Biological and pharmacological effects of hexahydrocurcumin, a metabolite of curcumin
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