The target is a total phenytoin level of 15-20 ug/mL, or an estimated free phenytoin level of 1.5-2 ug/mL after albumin correction (more on this below)
Then theres other evidence such as where tablets have been introduced to treat patients with Pernicious Anaemia doctors still keep on prescribing the injections and anyway, patients are easily able to purchase injectable B12 from other sources and treat themselves
You can choose syringes designed to deliver the medication either into muscle tissue or into fat tissue (subcutaneously)
No typical human dose has been established
Advantages of oral form over IM injection: Less nursing time on injections Less complexity of care Less discomfort/pain Less bleeding in patients who take anticoagulants Less costly according to some analyses Disadvantages of oral form over IM injection:: Greater risk of non-compliance In 1991, a survey done on Minneapolis internists led one commentary to conclude that oral vitamin B 12 replacement for pernicious anemia was one of medicines best kept secret. 18 In 1996, when the survey was repeated again in the same area, awareness and use of oral vitamin B 12 for pernicious anemia had increased substantially (019%), but the majority of doctors still remain unaware of this treatment option (61%)
The living tissue becomes further inflamed, and the tissue damage quickly involves the adjacent liver