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Nitric Oxide Modulation This peptide interacts with the nitric oxide system to regulate blood vessel function and reduce inflammation
Targets such as EGFRvIII (positive in ~20-30% of cases) display spatial heterogeneity and can be downregulated under therapeutic pressure, enabling outgrowth of antigen-negative clones after initial response
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Korkmaz OT, Ay H, Aytan N et al (2019) Vasoactive intestinal peptide decreases -amyloid accumulation and prevents brain atrophy in the 5xFAD mouse model of Alzheimers disease
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These include: Those with a history of cancer: IGF-1 can be involved in the growth of certain types of cancer
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