A more conservative, development-minded view would be: If youre eligible for an ARA-290 clinical trial targeting your condition, that is by far the most rational pathmonitored dosing, clean drug supply, and data generation that can help others

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( a ) GSEA analysis of upper vs lower tertiles ranked on overall survival, graph shows Normalised Enrichment Score (NES) for Poor Outcome patients
doi:10.33549/physiolres.934863 Kose S, Sozlu S, Bolukbasi H, Unsal N, Gezmen-Karadag M
Molecular Cell, 2006
Patients with primary hyperoxaluria type 2 have significant morbidity and require careful follow-up