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Low levels of insulin-like growth-factor-binding protein-1 (IGFBP-1) are prospectively associated with the incidence of type 2 diabetes and impaired glucose tolerance (IGT): the Sderkra Cardiovascular Risk Factor Study
Exp Clin Endocrinol Diabetes (2022) 130(4):23747
So we think that, yes, there is an absolute decrease in muscle mass, but there doesnt seem to be anything thats disproportionate per se
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Muskiet MHA, Tonneijck L, Smits MM, van Baar MJB, Kramer MHH, Hoorn EJ, et al
The Anti-Inflammatory Tripeptide in the KLOW Blend
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