In clinical trials, retatrutide has been studied as a once-weekly injection using gradual dose escalation
Ideal candidates for GLP-1 therapy include: Men with a BMI of 30 or higher, regardless of other health conditions Men with a BMI of 27+ who also have at least one weight-related condition such as hypertension, hypertension, dyslipidemia, insulin resistance, or sleep apnea ( 8 ) Men whove had difficulty maintaining long-term weight loss despite reasonable diet and exercise efforts GLP-1s may not be appropriate for men who: Have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 ( 9 ) Have a history of pancreatitis or certain gallbladder issues Are currently dealing with severe gastrointestinal conditions Are allergic to any component of the medication Before beginning any GLP-1 program, its important to undergo bloodwork and a comprehensive health assessment to ensure youre a good candidate

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While the total amount of weight you can lose on semaglutide is pretty significant studies show people can lose an average of 15-18.7% of their weight, depending on their dose, after a little more than a year it doesnt all happen at once
Question 2: What dose(s) did they test
It should only be used under appropriate medical guidance in settings where it is legally and clinically appropriate