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It was reported that the weight loss property of most GLP-1 analogs, except for semaglutide administered subcutaneously once weekly of smoother pharmacokinetics, is hampered by the therapeutic window because of the dose-dependent side-effects 10,11

Journal of Cosmetic Dermatology, 18(3), 728737

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When used together, they are often referred to as a growth hormone-releasing hormone (GHRH) analog and a growth hormone secretagogue combination