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We previously produced the App NL-G-F/NL-G-F -KI ( App NL-G-F ) mouse strain using genomic DNA of introns 15 to 17 of mouse APP, which humanized the A sequence, and introduced KM670/671NL (Swedish), I716F (Iberian), and E693G (Arctic) mutations 41
10.3748/wjg.v27.i25.3837 29 LiuZ.SunC.TaoR.XuX.XuL.ChengH.et al (2016)
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Some individuals experience minor improvements in their dizziness and weakness
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models
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