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CD8 + T cell function is bidirectionally regulated by ferroptosis, tumor cells weaken immunity by competing for cystine and CD36-mediated lipid peroxidation to induce T cell ferroptosis, whereas IFN- and related signals reverse this process by driving ferroptosis in tumor cells, thereby enhancing therapeutic efficacy

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Pollard C, Nguyen TP, Ng SP, Frank SJ, Garden AS, Gunn GB, Fuller CD, Beadle BM, Morrison WH, Shah SJ, Wang H, Tung S, Wang C, Ginsberg LD, Zafereo ME , Sturgis EM, Su SY, Hanna EY, Rosenthal DI, Phan J

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Johns County practice, the most requested therapies fall into a few categories