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Serious but rare adverse effects include pancreatitis, gallbladder disease, acute kidney injury (usually secondary to dehydration from gastrointestinal symptoms), and hypoglycemia when combined with insulin or sulfonylureas
They should never be used as an alternative to therapies and medication
But if you have nerve damage from your lack of B12, it could be permanent
Directions for Use: Dosage and Administration: Use as directed by a healthcare provider
This review study highlights the biological effects of different NAD+ boosters as well as the unique benefits of direct NAD+ administration over oral precursors because it bypasses gut and liver metabolism
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