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Clinically, 5-HT3 receptor antagonists (e.g., alosetron) (Savarino et al., 2022) and 5-HT4 receptor agonists (e.g., prucalopride) ( 4.2 Microbiota-hormones-ENS crosstalk The GI tract functions as a significant endocrine organ, primarily due to specialized epithelial cells known as EECs

10.3389/fphar.2018.00782 64 MaX.JiangY.WuA.ChenX.PiR.LiuM.et al (2010)

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Power analysis (G Power version 3.0.3) was carried out on both models in order to determine the number of mice required to see a 20% improvement in rotarod performance