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GLP-1 may help improve BBB function in these diseases by reducing oxidative stress and inflammation
Continuous use: ~18% reduction in heart attack, stroke, and death Stop the drug: 6 months +4% risk 1 year +14% 1.5 years benefit erased 2 years +22% risk It takes 3 years to build protection and ~11.5 years to lose it
Starting with lower doses (0.25 mg) and gradually increasing allows assessment of individual tolerance
Se inici un ensayo de fase II en humanos para la colitis ulcerosa, con resultados preliminares alentadores
10.1016/j.tem.2012.12.002 Trends Endocrinol
It is important to note that dosage alone does not determine effectiveness, as absorption, formulation type, and individual biological factors all influence outcomes
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