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The stacking is offered through some telehealth clinics on the basis of mechanism extrapolation and clinical practice experience

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Given that appetite and weight control will be key targets for an oral formulation, it is fortuitous that it is the stimulation of vagal afferents that has a direct impact on satiety effects of GLP1-RAs (Cork, 2018)

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Mol Cell Biochem 350:1327

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Both medications are effective treatments and can reduce blood glucose levels in different ways

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Doyle-Delgado K, Chamberlain JJ, Shubrook JH, Skolnik N, Trujillo J

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Here are the primary candidates and what the evidence shows for each

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