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At baseline, most patients (97%) were treated with one or more glucose-lowering medications, including metformin (76%), insulin (51%), SGLT-2i (27%), sulfonylurea (29%), and DPP-4i (23%) with CV disease and risk factors managed with lipid-lowering medications (89%), platelet-aggregation inhibitors including aspirin (77%), angiotensin converting enzyme inhibitors or angiotensin II receptor blockers (79%), and beta blockers (64%)
ClinicalTrials.gov (NIH): A Study of Retatrutide (LY3437943) in Participants With Overweight or Obesity (TRIUMPH-1 details)
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Results Literature Selection and Study Characteristics Among the 3055 articles obtained in the primary searches from MEDLINE, EMBASE, and CENTRAL databases and the 135 potentially relevant trials identified in ClinicalTrials.gov, a total of 28 published studies that met the inclusion criteria were included in the systematic review
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