Journal of Chromatography 311, 176-182
The process through which NAION destroys vision involves these sequential pathological events: Sudden blood supply disruption: Short posterior ciliary arteries feeding the optic nerve become blocked or experience severe flow reduction, starving nerve tissue Immediate nerve tissue death: Ischemic damage kills optic nerve cells within hours once dead, these neurons cannot regenerate Compartment syndrome: Initial swelling compresses remaining healthy nerve fibers in the confined scleral canal space, creating cascading damage Permanent structural changes: The optic nerve develops atrophy, with dead tissue replaced by glial scarring unable to transmit visual signals NAION commonly affects individuals with crowded optic discs or disc at risk, where cup-to-disc ratio measures 0.2 or less
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Many non-medical people (and apparently some medical people as well) seem to think peptides are some exciting new discovery in the world of medicine
For example, reduced levels of SCFAs (like butyrate, which is normally made by good bacteria) can weaken the BBB, making the brain more vulnerable to harmful substances
Here are the most common ones: The most common semaglutide side effects, which are nausea, appetite changes, and digestive discomfort, are systemic