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If you are comparing these medicines, the practical question is not only which one produced larger average results in studies

SUSTAIN-6 compared semaglutide and placebo in 3,297 people with type 2 diabetes and established cardiovascular disease, chronic kidney disease, or both, or who were aged over 60 years and had subclinical evidence of cardiovascular disease (persistent microalbuminuria or proteinuria, hypertension with left ventricular hypertrophy, left ventricular dysfunction by imaging, ankle/brachial index less than 0.9)

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Dr John Batsis, an associate professor of medicine at the University of North Carolina, noted that some of his patients who used similar weight loss treatments became frail and even suffered fractures