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doi: 10.3389/fnut.2025.1566498 Received 24 January 2025 Accepted 28 March 2025 Published 25 April 2025 Volume 12 - 2025 Edited by Iolanda Cioffi, University of Milan, Italy Reviewed by Valentina Ponzo, University of Turin, Italy Emily Fritz, Consultant, South Barrington, IL, United States Alissa Smethers, Temple University, United States Updates Copyright 2025 Johnson, Milstead, Thomas, McGlasson, Green, Kreider and Jones

Inflamm Bowel Dis (2006) 12(1):536.10.1097/01.MIB.0000195975.97673.f5 163 MoranGWLeslieFCMcLaughlinJT

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Reducing the enzymes activity decreases melanin synthesis, leading to the gradual fading of dark patches