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Clinical Comparisons: Does Dosage Drive Better Results

These modifications collectively address the major limitations of natural amylin - its tendency to aggregate into toxic fibrils, rapid degradation, and poor pharmacokinetic properties - while preserving and enhancing its beneficial metabolic effects

Patients with pre-existing cardiovascular disease, hypertension, or arrhythmia history should undergo baseline ECG before starting Wegovy and repeat monitoring if palpitations persist beyond 8 weeks

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