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Thought to make use of every vial before the expiry date
Drug Discovery Today 26:19721979
Planta 243:13091309
Initial studies used a redox probe, which allowed a measurement of ratios, but not absolute concentrations, and measured redox state throughout the secretory pathway rather than specifically in the ER (Hwang et al , 1992)
Patients with pre-existing cardiovascular disease should be monitored more closely, though Wegovy has demonstrated safety in this population
Despite potential savings for weight-loss jab users in some areas, the cost of the drugs is a concern for some
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