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Apparent differences smaller than 2-fold may not be biologically meaningful
Although there is evidence that DPP-4 inhibitors confer cardiovascular safety and renoprotection, the potential risks of hospitalization for heart failure and acute pancreatitis are disadvantages to their use as add-on therapy
95% CI, 0.26 to 2.04
The resulting oxidized form of GSH either reacts with another GSH molecule to form GSSG or with cysteine groups on cellular proteins to form protein GSH mixed disulfides, a process known as protein glutathionylation. This latter reaction can change the proteins structure and function, which can, in turn, evoke a functional change within the cell
Stankler L
D.MumawV
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