KPV is a small tripeptide, which makes it generally more stable than larger peptides
Tirzepatide is not indicated for type 1 diabetes and should be avoided during pregnancy
Abstracts Cuglievan B , Jen WY, Short NJ, Bataller A, DiNardo CD, Loghavi S, Daver N, MD, Farhat A, Hajjar GE, McCall D, Gibson A, Garcia M, Nunez C, Roth M, Kadia TM, Bazinet A, Jabbour E, Montalban-Bravo G, Ravandi F, Garcia-Manero G, Andreeff M , Kantarjian HM, Issa GC
One panel member, an endocrinologist, was absent from this discussion
For the evaluation of the effects of treatments on insulin sensitivity, insulin tolerance tests (ITT) were conducted 5 days after implementation of the GTTs, which allowed the proper recovery and washout of the animals
N Engl J Med 387 , 205216 (2022)